The Red Death is a late-game crisis in Civilization 6 that emerges when your empire amasses too many GPP-linked districts, wonders, and population clusters. This guide explains how the mechanic triggers, how the disease spreads across cities and districts, which buildings and quartiers are affected, and how to adapt your strategy to survive or even leverage the threat. Whether you are playing on standard, huge, or higher difficulties, understanding the Red Death helps you plan districts, manage adjacency, and time your growth.
